Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852546 | 0.89 | PTGS1 (0.36) | PTGS1CXCR1CXCR2GSTP1GSTM2 | |
| SCHEMBL9748003 | 0.84 | PTGS1 (0.36) | PTGS1CXCR1CXCR2GSTP1GSTM2 | |
| SCHEMBL10685641 | 0.81 | PTGS1 (0.39) | PTGS1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL9749147 | 0.76 | MAPK1 (0.40) | HPGDALDH1A1MAPTKMT2AHSD17B10 | |
| SCHEMBL9852499 | 0.73 | KMT2A (0.40) | PTGS1CXCR1CXCR2GSTP1GSTM2 | |
| SCHEMBL9748133 | 0.72 | HSD17B10 (0.32) | HPGDALDH1A1MAPTHSD17B10 | |
| SCHEMBL15737155 | 0.65 | KMT2A (0.43) | PTGS1CXCR1CXCR2GSTP1GSTM2 | |
| SCHEMBL12292 | 0.64 | CCNE1 (0.59) | PTGS1CCNE2CCNE1CDK2CCNB2 | |
| SCHEMBL6760169 | 0.64 | KDM4E (0.40) | PTGS1LMNAHTTKMT2A | |
| SCHEMBL9627350 | 0.63 | PTGS1 (0.40) | PTGS1CXCR1CXCR2GSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |