Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102725 | 0.87 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 | |
| SCHEMBL2956925 | 0.80 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 | |
| SCHEMBL2079708 | 0.80 | KEAP1 (0.53) | ALDH1A1L3MBTL1KEAP1MEN1KMT2A | |
| SCHEMBL19202478 | 0.80 | MAPT (0.48) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 | |
| SCHEMBL10348575 | 0.79 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 | |
| SCHEMBL5679908 | 0.79 | MAOA (0.53) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 | |
| SCHEMBL11814014 | 0.79 | KEAP1 (0.53) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 | |
| SCHEMBL11814983 | 0.78 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1MAOAMEN1KMT2A | |
| SCHEMBL8875574 | 0.78 | PTGER1 (0.54) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 | |
| SCHEMBL27876964 | 0.77 | MAPT (0.51) | ALDH1A1L3MBTL1KEAP1MAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740604-A | HYDRAZONE DYE INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1988-04-26 | — | — | US | disclosed |