Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102725 | 0.84 | ALDH1A1 (0.56) | KEAP1NFE2L2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL5679908 | 0.83 | MAOA (0.53) | KEAP1NFE2L2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL27876964 | 0.81 | MAPT (0.51) | KEAP1ALDH1A1L3MBTL1ADORA2AMAPT | |
| SCHEMBL11814983 | 0.79 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL10686141 | 0.79 | ALDH1A1 (0.50) | KEAP1NFE2L2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL431678 | 0.78 | MEN1 (0.53) | KEAP1NFE2L2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL16424117 | 0.78 | ADORA2A (0.57) | KEAP1NFE2L2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL2079708 | 0.77 | KEAP1 (0.53) | KEAP1NFE2L2ALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL2956925 | 0.77 | ALDH1A1 (0.56) | KEAP1ALDH1A1L3MBTL1MAPTMEN1 | |
| SCHEMBL19202478 | 0.77 | MAPT (0.48) | KEAP1NFE2L2ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960866-A | Process for preparing 1-aza-2-hydroxybenzanthrone | MONTEDISON S.P.A. (IT) | 1976-06-01 | — | — | US | disclosed |