SCHEMBL1068646

SCHEMBL1068646

O=C1c2c(ccc(O)c2O)OC(O)(c2ccccc2)C1(O)O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
MAPT P10636 4/20 0.35
RECQL P46063 4/20 0.35
MEN1 O00255 3/20 0.35
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 3/20 0.35
HPGD P15428 3/20 0.35
ALOX15 P16050 3/20 0.35
MAOA P21397 3/20 0.35
MAPK1 P28482 3/20 0.35
KMT2A Q03164 3/20 0.35
HSD17B10 Q99714 3/20 0.35
ALOX12 P18054 2/20 0.35
DAPK1 P53355 2/20 0.35
CYP1B1 Q16678 2/20 0.35
APEX1 P27695 2/20 0.35
BCL2 P10415 1/20 0.35
MCL1 Q07820 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GNG2 P59768 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30658588 1.00 KDM4E (0.35) KDM4EMAPTRECQLMEN1ALDH1A1
SCHEMBL27441448 0.84 PLK1 (0.40) KDM4EMAPTRECQLMEN1ALDH1A1
SCHEMBL30689853 0.84 CA1 (0.39) KDM4EMAPTRECQLMEN1ALDH1A1
SCHEMBL3698500 0.84 CA1 (0.39) KDM4EMAPTRECQLMEN1ALDH1A1
SCHEMBL28686647 0.82 RIPK1 (0.33) KDM4EMAPTRECQLMEN1ALDH1A1
Flavanone SCHEMBL3438656 0.82 MAOB (0.53) KDM4EMAPTMEN1CYP3A4MAOA
SCHEMBL725961 0.80 MEN1 (0.31) KDM4EMAPTRECQLMEN1ALDH1A1
SCHEMBL29740777 0.76 HSP90AA1 (0.34) MAPTRECQLMEN1ALDH1A1CYP3A4
SCHEMBL727643 0.73 MAPT (0.40) MAPTRECQLALDH1A1CYP3A4HPGD
SCHEMBL28515636 0.73 ADAMTS4 (0.33) RECQLALDH1A1HPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109172640-A Application of the flavones ingredient in the drug for preparing anti-oral cavity bacterial diseases in paper mulberry 中国科学院昆明植物研究所 2019-01-11 CN claimed
EP-2875359-A2 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS Charles R Drew University of Medicine and Science (US) 2015-05-27 EP claimed
WO-2013149258-A2 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING METABOLIC SYNDROME DISORDERS Charles Drew University of Medicine and Science (US) 2013-10-03 WO claimed
US-7338791-B2 Introducing the set of genes into a heterologous host cell, allowing growth of the cells in a suitable medium such that the expression of the genes results in production of enzymes; culturing the cell under conditions permitting the synthesis of the flavonoid by the cells; isolating s flavonoids THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-03-04 US claimed
WO-2006024545-A1 FUSED BICYCLIC NATURAL COMPOUNDS AND THEIR USE AS INHIBITORS OF PARP AND PARP-MEDIATED INFLAMMATORY PROCESSES STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) 2006-03-09 WO claimed
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities THE BROAD INSTITUTE, INC. (US) 2026-03-17 US disclosed
US-20250376656-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-12-11 US disclosed
US-20240263203-A1 RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES IPTECTOR ASSETS APS (DK) 2024-08-08 US disclosed
WO-2023230574-A1 ENGINEERED PHENYLALANINE AMMONIA LYASE AND TYROSINE AMMONIA LYASE ENZYMES FOR PRODUCING AROMATIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2023-11-30 WO disclosed
US-20220228190-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-07-21 US disclosed
EP-3906301-A1 RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES Barrit Sarl (FR) 2021-11-10 EP disclosed
CN-113384622-A Application of semen plantaginis extract in preparing medicine for treating myocardial hypertrophy 上海中医药大学 2021-09-14 CN disclosed
US-5569832-A DIHYDROKAEMFEROL (DHK) HYDROXYLATING ENZYME, FLOWER COLOR INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 1996-10-29 US disclosed
EP-0703982-A4 1996-04-17 EP disclosed
EP-0703982-A1 TRANSGENIC FLOWERING PLANTS INTERNATIONAL FLOWER DEVELOPMENTS Pty. Ltd. (AU) 1996-04-03 EP disclosed
WO-1994028140-A1 TRANSGENIC FLOWERING PLANTS INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 1994-12-08 WO disclosed
US-5349125-A Flower pigmentation INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 1994-09-20 US disclosed
CN-1071456-A Genetic sequences encoding flavonoid pathway enzymes and uses thereof INT FLOWER DEV PTY LTD (AU) 1993-04-28 CN disclosed
WO-1993001290-A1 GENETIC SEQUENCES ENCODING FLAVONOID PATHWAY ENZYMES AND USES THEREFOR INTERNATIONAL FLOWER DEVELOPMENTS PTY. LTD. (AU) 1993-01-21 WO disclosed
EP-0522880-A2 Genetic sequences encoding flavonoid pathway enzymes and uses therefor INTERNATIONAL FLOWER DEVELOPMENTS Pty. Ltd. (AU) 1993-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities STUB1, SAMM50, CD14 KDM4E 2737/4885MAPT 1771/4885RECQL 1453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.