Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688906 | 0.91 | ALDH1A1 (0.42) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL9689854 | 0.85 | HSD17B10 (0.50) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL9824624 | 0.83 | DRD1 (0.42) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL9824685 | 0.82 | MAPT (0.43) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL10691974 | 0.80 | HSD17B10 (0.54) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL10686314 | 0.76 | ATM (0.44) | MAPTCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9825048 | 0.75 | KEAP1 (0.40) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL9672675 | 0.75 | ADORA3 (0.65) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL9674762 | 0.74 | ADORA3 (0.64) | HSD17B10MAPTTSHRALDH1A1LMNA | |
| SCHEMBL9824964 | 0.73 | CACNA1C (0.49) | MAPTTSHRALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727082-A | CARDIOVASCULAR DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| EP-0167371-A2 | Dihydropyridine compounds, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-01-08 | — | — | EP | disclosed |