Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Benzylmethylamine SCHEMBL10694644 | 0.81 | ALDH1A1 (0.37) | NOTUMPOLBTP53MEN1KMT2A | |
| SCHEMBL10689216 | 0.79 | HTR2A (0.39) | NOTUMHTR2A | |
| SCHEMBL29187823 | 0.79 | NOTUM (0.47) | NOTUMPOLBTP53MEN1KMT2A | |
| SCHEMBL10694640 | 0.77 | ALDH1A1 (0.44) | POLBTP53MEN1KMT2ALMNA | |
| SCHEMBL10509662 | 0.76 | ADRA1D (0.51) | MEN1KMT2AALDH1A1HTR2A | |
| SCHEMBL10689206 | 0.75 | NOTUM (0.40) | NOTUMPOLBTP53MEN1KMT2A | |
| SCHEMBL10507943 | 0.73 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL10689221 | 0.72 | NOTUM (0.41) | NOTUMPOLBTP53MEN1KMT2A | |
| SCHEMBL10837950 | 0.71 | ADRA1D (0.47) | — | |
| SCHEMBL10507820 | 0.69 | ADRA1D (0.45) | ALDH1A1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792559-A | 1,2,3,4-tetrahydroquinoline substituted 5-aminopentanenitrile compounds and their use as calcium modulators | ADIR ET COMPAGNIE (FR) | 1988-12-20 | — | — | US | disclosed |