Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689213 | 0.79 | NOTUM (0.39) | HTR2ANOTUM | |
| SCHEMBL29187823 | 0.79 | NOTUM (0.47) | NOTUM | |
| SCHEMBL10689206 | 0.75 | NOTUM (0.40) | NOTUM | |
| SCHEMBL10689221 | 0.75 | NOTUM (0.41) | NOTUM | |
| N-Benzylmethylamine SCHEMBL10694644 | 0.74 | ALDH1A1 (0.37) | NOTUM | |
| SCHEMBL10694640 | 0.73 | ALDH1A1 (0.44) | — | |
| SCHEMBL10509662 | 0.72 | ADRA1D (0.51) | HTR2A | |
| SCHEMBL10507943 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL10837950 | 0.67 | ADRA1D (0.47) | — | |
| SCHEMBL15807603 | 0.66 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792559-A | 1,2,3,4-tetrahydroquinoline substituted 5-aminopentanenitrile compounds and their use as calcium modulators | ADIR ET COMPAGNIE (FR) | 1988-12-20 | — | — | US | disclosed |