Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187823 | 0.79 | NOTUM (0.47) | NOTUMCYP2D6TP53LMNAMEN1 | |
| SCHEMBL10689213 | 0.75 | NOTUM (0.39) | NOTUMTP53LMNAMEN1KMT2A | |
| SCHEMBL10689216 | 0.75 | HTR2A (0.39) | NOTUM | |
| SCHEMBL10689221 | 0.73 | NOTUM (0.41) | NOTUMCYP2D6TP53LMNAMEN1 | |
| N-Benzylmethylamine SCHEMBL10694644 | 0.70 | ALDH1A1 (0.37) | NOTUMTP53LMNAMEN1KMT2A | |
| SCHEMBL30826397 | 0.66 | ALDH1A1 (0.37) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL29187830 | 0.66 | ALDH1A1 (0.37) | MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL30573244 | 0.66 | NOTUM (0.53) | NOTUMCYP2D6TP53LMNAMEN1 | |
| SCHEMBL718605 | 0.66 | NOTUM (0.53) | NOTUMCYP2D6TP53LMNAMEN1 | |
| SCHEMBL10694640 | 0.65 | ALDH1A1 (0.44) | CYP2D6TP53LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792559-A | 1,2,3,4-tetrahydroquinoline substituted 5-aminopentanenitrile compounds and their use as calcium modulators | ADIR ET COMPAGNIE (FR) | 1988-12-20 | — | — | US | disclosed |