Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694821 | 0.89 | SCN5A (0.36) | ACSS2 | |
| SCHEMBL10693333 | 0.89 | IDH1 (0.36) | — | |
| SCHEMBL10694763 | 0.89 | KDM4E (0.33) | KDM4EALDH1A1HPGDACSS2 | |
| SCHEMBL10693958 | 0.82 | SCN5A (0.36) | KDM4EALDH1A1ACSS2 | |
| SCHEMBL10695710 | 0.80 | PDE10A (0.39) | KDM4EALDH1A1HPGD | |
| SCHEMBL10690618 | 0.78 | MEN1 (0.42) | KDM4E | |
| SCHEMBL10690077 | 0.76 | KMT2A (0.30) | ALDH1A1HPGD | |
| SCHEMBL10693113 | 0.74 | KCNH2 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL10602397 | 0.73 | ATP4A (0.35) | TRPV1PRKCA | |
| SCHEMBL10691766 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |