SCHEMBL10690670

SCHEMBL10690670

COc1ccc(C(=O)c2ccc(N(C)c3ccccc3)cc2C(=O)O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTC4S Q16873 8/20 0.61
LMNA P02545 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
CYP3A4 P08684 1/20 0.52
TSHR P16473 1/20 0.52
HPGD P15428 2/20 0.50
ALDH1A1 P00352 1/20 0.50
PGR P06401 1/20 0.50
CYP2D6 P10635 1/20 0.50
SLC6A2 P23975 1/20 0.50
PDE4A P27815 1/20 0.50
MAPK1 P28482 1/20 0.50
HRH1 P35367 1/20 0.50
HTT P42858 1/20 0.50
SLC6A3 Q01959 1/20 0.50
PDE4D Q08499 1/20 0.50
NPC1 O15118 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10693522 0.91 LTC4S (0.60) LTC4SLMNACYP1A2CYP2C19KMT2A
SCHEMBL10531019 0.91 LTC4S (0.62) LTC4SLMNACYP1A2CYP2C19KMT2A
SCHEMBL7848711 0.87 LMNA (0.64) LTC4SLMNACYP1A2CYP2C19KMT2A
SCHEMBL9806081 0.85 ACHE (0.61) LMNACYP1A2CYP2C19KMT2AMEN1
SCHEMBL12757166 0.82 ACHE (0.61) LMNACYP1A2CYP2C19KMT2AMEN1
SCHEMBL9312633 0.81 LMNA (0.64) LTC4SLMNACYP1A2CYP2C19KMT2A
SCHEMBL10692514 0.81 KMT2A (0.52) LTC4SLMNACYP1A2CYP2C19KMT2A
SCHEMBL4124832 0.80 NPC1 (0.68) LMNACYP1A2CYP2C19KMT2AMEN1
SCHEMBL3480945 0.79 ALDH1A1 (0.71) LMNACYP1A2CYP2C19KMT2AHPGD
SCHEMBL10690638 0.79 ACHE (0.53) LTC4SLMNACYP1A2CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed