Triethylene Glycol

Triethylene Glycol

SCHEMBL10691657

Cc1cc(C)c(S(N)(=O)=O)c(C)c1.OCCOCCOCCO

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.41
F2 P00734 3/20 0.41
PRSS1 P07477 3/20 0.41
PRSS2 P07478 3/20 0.41
PRSS3 P35030 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP8 P22894 1/20 0.41
MMP13 P45452 1/20 0.41
ALDH1A1 P00352 2/20 0.40
CA12 O43570 2/20 0.39
CA7 P43166 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
KDM4E B2RXH2 1/20 0.39
PDIA6 Q15084 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113366 0.80 CA1 (0.52) F2PRSS1PRSS2PRSS3CA1
SCHEMBL1169963 0.72 HTR1A (0.45) HTR1AALDH1A1MEN1KMT2AMAPK1
SCHEMBL1170455 0.72 HTR1A (0.45) HTR1AALDH1A1MEN1KMT2AMAPK1
Beta-Alanine SCHEMBL5777756 0.70 FABP4 (0.50) F2PRSS1PRSS2PRSS3CA1
Triethylene Glycol SCHEMBL10695052 0.69 CA1 (0.45) CA1CA2ALDH1A1CA12CA7
SCHEMBL9218786 0.69 ALDH1A1 (0.50) F2PRSS1PRSS2PRSS3CA1
SCHEMBL1322793 0.68 CA2 (0.40) F2PRSS1PRSS2PRSS3CA1
Di(Hydroxyethyl)Ether SCHEMBL28472606 0.66 TSHR (0.59) CA1CA2ALDH1A1CA12CA7
SCHEMBL9308498 0.66 TP53 (0.49) HTR1AALDH1A1MEN1KMT2AMAPK1
Pentaethylene Glycol SCHEMBL7519778 0.66 ALDH1A1 (0.49) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4764570-A MODIFYING MELAMINE-FORMALDEHYDE RESINS CASSELLA AKTIENGESELLSCHAFT (DE) 1988-08-16 US disclosed