Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690887 | 0.87 | L3MBTL1 (0.64) | NPC1RAB9AL3MBTL1KMT2ALMNA | |
| SCHEMBL10693682 | 0.85 | L3MBTL1 (0.50) | RAB9AL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL4242010 | 0.84 | L3MBTL1 (0.56) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL10690936 | 0.81 | ALDH1A1 (0.56) | RAB9AL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL10691781 | 0.81 | SMN1; SMN2 (0.60) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL22966593 | 0.76 | L3MBTL1 (0.62) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL10693458 | 0.75 | FPR1 (0.48) | L3MBTL1LMNAALDH1A1HPGD | |
| SCHEMBL10692512 | 0.75 | HDAC3 (0.63) | MEN1KMT2ALMNAALDH1A1HPGD | |
| SCHEMBL19879879 | 0.74 | HPGD (0.60) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6072206 | 0.73 | KMT2A (0.70) | NPC1RAB9AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |