Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | THPO | P40225 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691974 | 0.84 | HSD17B10 (0.54) | LMNAALDH1A1AGTR1RAB9AHSD17B10 | |
| SCHEMBL10692954 | 0.82 | ADORA3 (0.53) | LMNAALDH1A1AGTR1HSD17B10HIF1A | |
| SCHEMBL7350843 | 0.81 | MAPT (0.70) | LMNARAB9AHIF1ACYP1A2CYP3A4 | |
| SCHEMBL10918103 | 0.81 | MAPT (0.70) | LMNARAB9AHIF1ACYP1A2CYP3A4 | |
| SCHEMBL10567349 | 0.81 | ADORA3 (0.52) | LMNAALDH1A1AGTR1HSD17B10HIF1A | |
| SCHEMBL9689854 | 0.79 | HSD17B10 (0.50) | LMNAALDH1A1AGTR1HSD17B10HIF1A | |
| SCHEMBL7346372 | 0.79 | HSD17B10 (0.62) | LMNAALDH1A1AGTR1HSD17B10HIF1A | |
| SCHEMBL7347242 | 0.79 | ADORA3 (0.69) | LMNAALDH1A1AGTR1HSD17B10HIF1A | |
| SCHEMBL7279871 | 0.78 | MAPT (0.66) | LMNAHIF1ACYP1A2CYP3A4MAPT | |
| SCHEMBL10742637 | 0.78 | MAPT (0.69) | LMNAHIF1ACYP1A2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727082-A | CARDIOVASCULAR DISORDERS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-02-23 | — | — | US | disclosed |