Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2521366 | 0.90 | PTPN1 (0.38) | PTPN1CYP3A4CYP1A2C5AR1KDM4E | |
| SCHEMBL89548 | 0.83 | ALDH1A1 (0.50) | PTPN1ALOX5CYP3A4CYP1A2C5AR1 | |
| SCHEMBL8946208 | 0.83 | CYP1A2 (0.41) | PTPN1ALOX5CYP3A4CYP1A2C5AR1 | |
| SCHEMBL278676 | 0.81 | PTPN1 (0.47) | PTPN1CYP3A4KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL6382727 | 0.81 | PTPN1 (0.37) | PTPN1CYP3A4CYP1A2C5AR1KDM4E | |
| SCHEMBL655212 | 0.80 | KDM4E (0.46) | PTPN1ALOX5CYP3A4C5AR1KDM4E | |
| SCHEMBL21084683 | 0.80 | PTPN1 (0.44) | PTPN1ALOX5CYP3A4CYP1A2C5AR1 | |
| SCHEMBL14989370 | 0.80 | PTPN1 (0.33) | PTPN1KDM4E | |
| SCHEMBL83996 | 0.78 | AKR1C3 (0.46) | PTPN1CYP3A4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL11297700 | 0.78 | CYP1A2 (0.41) | PTPN1CYP1A2C5AR1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63258836-A | — | — | None | — | — | JP | disclosed |
| JP-S63258836-A | PRODUCTION OF ETHENE DERIVATIVE | RICOH CO LTD | 1988-10-26 | — | — | JP | disclosed |