SCHEMBL8946208

SCHEMBL8946208

C=CCN(CC=C)c1ccccc1C(=S)c1ccccc1N(CC=C)CC=C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
PTPN1 P18031 1/20 0.40
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP3A4 P08684 1/20 0.34
C5AR1 P21730 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
ALOX12 P18054 1/20 0.34
CCR6 P51684 1/20 0.34
GAA P10253 1/20 0.33
KMT2A Q03164 3/20 0.33
ALOX5 P09917 1/20 0.32
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
KDM4E B2RXH2 2/20 0.31
MEN1 O00255 2/20 0.31
POLB P06746 2/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11297700 0.90 CYP1A2 (0.41) CYP1A2PTPN1ALDH1A1SMN1; SMN2C5AR1
SCHEMBL10692029 0.83 PTPN1 (0.43) CYP1A2PTPN1ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL89548 0.81 ALDH1A1 (0.50) CYP1A2PTPN1ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL278676 0.80 PTPN1 (0.47) PTPN1ALDH1A1SMN1; SMN2CYP3A4HPGD
SCHEMBL655212 0.79 KDM4E (0.46) PTPN1ALDH1A1SMN1; SMN2CYP3A4C5AR1
SCHEMBL21084683 0.79 PTPN1 (0.44) CYP1A2PTPN1ALDH1A1SMN1; SMN2CYP3A4
Hydrochloric Acid SCHEMBL27897977 0.79 PTPN1 (0.46) PTPN1ALDH1A1SMN1; SMN2CYP3A4HPGD
SCHEMBL2521366 0.77 PTPN1 (0.38) CYP1A2PTPN1ALDH1A1SMN1; SMN2CYP3A4
SCHEMBL83996 0.76 AKR1C3 (0.46) PTPN1ALDH1A1SMN1; SMN2CYP3A4LMNA
SCHEMBL6382727 0.76 PTPN1 (0.37) CYP1A2PTPN1ALDH1A1SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8053485-A None JP disclosed
JP-H0853485-A METHOD FOR SELECTIVELY ACETALIZING SACCHARIDES AGENCY OF IND SCIENCE & TECHNOL 1996-02-27 JP disclosed