SCHEMBL89548

SCHEMBL89548

C=CCN(CC=C)c1ccccc1C(=O)c1ccccc1N(CC=C)CC=C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
TSHR P16473 3/20 0.50
TP53 P04637 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
PTPN1 P18031 1/20 0.45
CYP3A4 P08684 1/20 0.42
ALOX5 P09917 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
POLB P06746 1/20 0.37
C5AR1 P21730 1/20 0.37
CYP1A2 P05177 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 1/20 0.37
LIG1 P18858 1/20 0.35
LMNA P02545 1/20 0.34
ALOX12 P18054 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11767364 0.92 AKR1C3 (0.44) ALDH1A1SMN1; SMN2TSHRTP53GAA
SCHEMBL83996 0.90 AKR1C3 (0.46) ALDH1A1SMN1; SMN2TSHRTP53GAA
SCHEMBL278676 0.87 PTPN1 (0.47) ALDH1A1SMN1; SMN2TSHRMAPTPTPN1
SCHEMBL655212 0.86 KDM4E (0.46) ALDH1A1SMN1; SMN2TSHRTP53GAA
SCHEMBL21084683 0.86 PTPN1 (0.44) ALDH1A1SMN1; SMN2TSHRTP53GAA
SCHEMBL11223527 0.84 KMT2A (0.38) ALDH1A1SMN1; SMN2TSHRTP53GAA
SCHEMBL10692029 0.83 PTPN1 (0.43) ALDH1A1SMN1; SMN2TSHRTP53GAA
SCHEMBL8946208 0.81 CYP1A2 (0.41) ALDH1A1SMN1; SMN2GAAMAPTPTPN1
SCHEMBL11120795 0.80 HPGD (0.59) ALDH1A1SMN1; SMN2TP53MAPTCYP3A4
SCHEMBL2538164 0.80 CYP3A4 (0.68) ALDH1A1SMN1; SMN2TSHRGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534839-B2 Sequentially terminated elastomers BRIDGESTONE CORPORATION (JP) 2009-05-19 US claimed
JP-2007500281-A 2007-01-11 JP claimed
US-20060135701-A1 Hysteresis elastomeric compositions comprising sequentially terminated polymers BRIDGESTONE CORPORATION (JP) 2006-06-22 US claimed
EP-1631596-A1 IMPROVED HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING SEQUENTIALLY TERMINATED POLYMERS Bridgestone Corporation (JP) 2006-03-08 EP claimed
WO-2004111094-A1 IMPROVED HYSTERESIS ELASTOMERIC COMPOSITIONS COMPRISING SEQUENTIALLY TERMINATED POLYMERS BRIDGESTONE CORPORATION (JP) 2004-12-23 WO claimed
EP-0203393-B1 CURABLE COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-07-12 EP claimed
US-4778859-A Tetramine derived polyimide with pendant unsaturation, and various photosensitive compositions therefrom ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-10-18 US claimed
EP-0203393-A1 Curable composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-12-03 EP claimed
JP-60078443-A None JP disclosed
JP-6003820-A None JP disclosed
EP-4378928-A1 NAPHTHALENE DITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION METHODS AND USES FOR SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-06-05 EP disclosed
WO-2023195346-A1 ULTRAVIOLET ABSORBENT 大阪ガスケミカル株式会社 2023-10-12 WO disclosed
WO-2023169352-A1 BENZOPHENONE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF 艾坚蒙(安庆)科技发展有限公司 2023-09-14 WO disclosed
US-20230288748-A1 LIGHT ABSORPTION FILTER, OPTICAL FILTER, SELF-LUMINOUS DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE, AND MANUFACTURING METHOD FOR OPTICAL FILTER FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
EP-0127574-A2 Light cross-linkable composition CIBA-GEIGY AG (CH) 1984-12-05 EP disclosed
EP-0126029-A2 Image-forming process CIBA-GEIGY AG (CH) 1984-11-21 EP disclosed
EP-0102921-A2 Process for making images from liquid substances CIBA-GEIGY AG (CH) 1984-03-14 EP disclosed
US-4276352-A Reinforced composites containing unsaturated polyimide resins CIBA-GEIGY CORPORATION (US) 1981-06-30 US disclosed
US-4254012-A Reinforced composites containing cyanato resins CIBA-GEIGY CORPORATION (US) 1981-03-03 US disclosed
US-4252593-A Method of preparing reinforced composites CIBA-GEIGY CORPORATION (US) 1981-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230288748-A1 LIGHT ABSORPTION FILTER, OPTICAL FILTER, SELF-LUMINOUS DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE, AND MANUFACTURING METHOD FOR OPTICAL FILTER NLRP1, NLRP3, STRA6 ALDH1A1 293/4885SMN1; SMN2 4446/4885TSHR 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.