Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89548 | 0.86 | ALDH1A1 (0.50) | PTPN1ALDH1A1CYP3A4HPGDCYP1A2 | |
| SCHEMBL278676 | 0.84 | PTPN1 (0.47) | PTPN1ALDH1A1ALOX15CYP3A4HPGD | |
| SCHEMBL655212 | 0.83 | KDM4E (0.46) | PTPN1ALDH1A1CYP3A4HPGDALOX5 | |
| Hydrochloric Acid SCHEMBL27897977 | 0.83 | PTPN1 (0.46) | PTPN1ALDH1A1ALOX15CYP3A4HPGD | |
| SCHEMBL10692029 | 0.80 | PTPN1 (0.43) | PTPN1ALDH1A1CYP3A4HPGDCYP1A2 | |
| SCHEMBL83996 | 0.80 | AKR1C3 (0.46) | PTPN1ALDH1A1CYP3A4HPGDPKM | |
| Benzophenone SCHEMBL27852184 | 0.79 | ALDH1A1 (0.45) | PTPN1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL11767364 | 0.79 | AKR1C3 (0.44) | PTPN1ALDH1A1ALOX15CYP3A4POLB | |
| SCHEMBL8946208 | 0.79 | CYP1A2 (0.41) | PTPN1ALDH1A1CYP3A4HPGDCYP1A2 | |
| SCHEMBL2538164 | 0.78 | CYP3A4 (0.68) | PTPN1ALDH1A1CYP3A4ALOX5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059939-B2 | Dicyclopentadiene derivatives and polymers thereof | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2021-07-13 | — | — | US | disclosed |
| US-20190202976-A1 | DICYCLOPENTADIENE DERIVATIVES AND POLYMERS THEREOF | B.G. NEGEV TECHNOLOGIES & APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2019-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11059939-B2 | Dicyclopentadiene derivatives and polymers thereof | DHPS, UROD, DCPS | PTPN1 4737/4885ALDH1A1 656/4885ALOX15 192/4885 |
| US-20190202976-A1 | DICYCLOPENTADIENE DERIVATIVES AND POLYMERS THEREOF | DHPS, UROD, DCPS | PTPN1 4737/4885ALDH1A1 656/4885ALOX15 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.