SCHEMBL10692508

SCHEMBL10692508

COc1cccc2c1Cc1cccc(Cl)c1C2=O

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP19A1 P11511 2/20 0.46
AR P10275 1/20 0.45
ACHE P22303 1/20 0.43
TYR P14679 1/20 0.43
USP2 O75604 1/20 0.42
DUSP3 P51452 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
EGFR P00533 1/20 0.42
PIM1 P11309 1/20 0.42
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7029795 0.83 NSD2 (0.40) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL20594366 0.80 KDM4E (0.68) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL16569613 0.76 CYP19A1 (0.56) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL29339250 0.76 KDM4E (0.49) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL29522447 0.75 MAOA (0.61) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL6902816 0.75 MAOA (0.61) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL6906412 0.74 ALDH1A1 (0.58) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL11698389 0.73 TYR (0.53) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL8854649 0.73 DRD2 (0.54) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL7103871 0.72 TSHR (0.57) ALDH1A1MAPTMEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4792551-A 9-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents SYNTEX (U.S.A.) INC. (US) 1988-12-20 US disclosed
EP-0132351-A2 9-Anthryloxyaminoalkanes and related compounds, processes for their preparation and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1985-01-30 EP disclosed