Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22875491 | 0.81 | CTSL (1.00) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL942176 | 0.81 | CTSL (1.00) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL942177 | 0.81 | CTSL (1.00) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL22056640 | 0.78 | CTSL (0.72) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9656092 | 0.76 | RAB9A (0.76) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9656096 | 0.76 | RAB9A (0.76) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12562236 | 0.74 | HKDC1 (0.46) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12562263 | 0.74 | LMNA (0.53) | CTSLRAB9ANPC1ALDH1A1HTT | |
| SCHEMBL10690224 | 0.73 | ATM (0.64) | RAB9ANPC1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL12562258 | 0.73 | L3MBTL1 (0.38) | CTSLRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4719221-A | ANTIPROTOZOA AGENTS | BURROUGHS WELLCOME CO. (US) | 1988-01-12 | — | — | US | disclosed |