SCHEMBL309694

SCHEMBL309694

NS(=O)(=O)c1ccc(Cc2ccc(S(N)(=O)=O)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.73
CA1 P00915 15/20 0.73
CA9 Q16790 14/20 0.73
CA12 O43570 13/20 0.73
CA14 Q9ULX7 10/20 0.73
CA4 P22748 5/20 0.70
CA6 P23280 5/20 0.70
CA5A P35218 5/20 0.70
CA7 P43166 5/20 0.70
CA5B Q9Y2D0 5/20 0.70
MAPT P10636 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.57
USP2 O75604 1/20 0.56
TSHR P16473 1/20 0.56
CA13 Q8N1Q1 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
AGO2 Q9UKV8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamide SCHEMBL5585371 0.97 CA2 (0.70) CA2CA1CA9CA12CA14
SCHEMBL10690610 0.91 CA2 (0.89) CA2CA1CA9CA12CA14
SCHEMBL27816697 0.89 CA2 (0.75) CA2CA1CA9CA12CA14
SCHEMBL27959272 0.87 CA2 (0.59) CA2CA1CA9CA12CA14
SCHEMBL202948 0.83 CA2 (0.81) CA2CA1CA9CA12CA14
Mafenide SCHEMBL41628 0.82 CA2 (1.00) CA2CA1CA9CA12CA14
SCHEMBL1804376 0.82 CA2 (0.67) CA2CA1CA9CA12CA14
Mafenide SCHEMBL9295695 0.82 CA2 (1.00) CA2CA1CA9CA12CA14
SCHEMBL14505689 0.80 CA2 (0.64) CA2CA1CA9CA12CA14
SCHEMBL13256756 0.80 CA2 (0.64) CA2CA1CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
US-12605384-B2 Uses INTRA-CELLULAR THERAPIES, INC. (US) 2026-04-21 US disclosed
EP-3746081-B1 PDE1 INHIBITORS FOR USE TO TREAT CARDIAC FAILURE AND CARDIOTOXICITY INTRA CELLULAR THERAPIES INC (US) 2026-04-01 EP disclosed
US-20260049314-A1 ANTISENSE OLIGONUCLEOTIDE-BASED ANTI-FIBROTIC THERAPEUTICS UNIVERSITY OF ROCHESTER (US) 2026-02-19 US disclosed
EP-4581143-A1 ANTISENSE OLIGONUCLEOTIDE-BASED ANTI-FIBROTIC THERAPEUTICS University of Rochester (US) 2025-07-09 EP disclosed
US-20250066790-A1 ANTISENSE OLIGONUCLEOTIDES FOR MODIFYING PROTEIN EXPRESSION UNIVERSITY OF ROCHESTER 2025-02-27 US disclosed
US-20250018009-A1 SERUM RESPONSE FACTOR REGENERATES SENESCENT CELLS UNIVERSITY OF HOUSTON SYSTEM (US) 2025-01-16 US disclosed
US-20250019702-A1 GATA4-TARGETED THERAPEUTICS FOR TREATMENT OF CARDIAC HYPERTROPHY UNIVERSITY OF ROCHESTER 2025-01-16 US disclosed
EP-3542160-B1 INHIBITORS OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE FOR TREATING CARDIOVASCULAR AND PULMONARY CONDITIONS ICHOR LLC (US) 2025-01-01 EP disclosed
EP-4444881-A2 GATA4-TARGETED THERAPEUTICS FOR TREATMENT OF CARDIAC HYPERTROPHY University of Rochester (US) 2024-10-16 EP disclosed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP disclosed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO disclosed
US-6024976-A TRANSDERMAL DRUG DELIVERY WITH PRESSURE SENSITIVE ADHESIVE COMPOSITION OF POLYVINYLPYRROLIDONE WITH DRUG IN MULTILAYER PATCH NOVEN PHARMACEUTICALS, INC. (US) 2000-02-15 US disclosed
US-5719197-A DRUG DELIVERY NOVEN PHARMACEUTICALS, INC. (US) 1998-02-17 US disclosed
US-5656286-A BLEND OF TWO POLYMERS; PRESSURE SENSITIVE ADHESIVE NOVEN PHARMACEUTICALS, INC. (US) 1997-08-12 US disclosed
WO-1996040084-A1 COMPOSITIONS AND METHODS FOR USE OF PRESSURE SENSITIVE ADHESIVE TRANSDERMAL DEVICES CONTAINING A BIOADHESIVE HUMECTANT NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
WO-1996040086-A2 COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF PHARMACEUTICALLY ACTIVE AGENTS NOVEN PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
US-5446070-A Flexible, finite, bioadhesive, therapeutical agent in solid form NOVER PHARMACEUTICALS, INC. (US) 1995-08-29 US disclosed
US-4855289-A Combination of two active substances WESTER PER O (SE) 1989-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049314-A1 ANTISENSE OLIGONUCLEOTIDE-BASED ANTI-FIBROTIC THERAPEUTICS UPF1, HNRNPF, RNMT CA2 4725/4885CA1 4883/4885CA9 4535/4885
US-20250019702-A1 GATA4-TARGETED THERAPEUTICS FOR TREATMENT OF CARDIAC HYPERTROPHY UPF1, TNNI3, TNNT2 CA2 3850/4885CA1 4765/4885CA9 4815/4885
US-12605384-B2 Uses PDE2A, NPR1, PDE7A CA2 997/4885CA1 3340/4885CA9 2348/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.