Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688445 | 0.74 | MAOA (0.43) | ALDH1A1CYP1A2 | |
| SCHEMBL10692962 | 0.73 | ALDH1A1 (0.46) | RAB9ANPC1NPSR1MAPTALDH1A1 | |
| SCHEMBL2188139 | 0.68 | SRD5A2 (0.66) | RAB9ANPC1MAPTALDH1A1ATM | |
| SCHEMBL30738988 | 0.68 | SRD5A2 (0.66) | RAB9ANPC1MAPTALDH1A1ATM | |
| SCHEMBL2186803 | 0.68 | SRD5A2 (0.66) | RAB9ANPC1MAPTALDH1A1ATM | |
| SCHEMBL28779200 | 0.67 | MAOA (0.59) | RAB9ANPC1NPSR1MAPTALDH1A1 | |
| SCHEMBL6132031 | 0.65 | NPSR1 (0.90) | RAB9ANPC1NPSR1MAPTALDH1A1 | |
| SCHEMBL7816239 | 0.65 | SRD5A2 (0.81) | RAB9ANPC1NPSR1MAPTALDH1A1 | |
| SCHEMBL26499247 | 0.65 | NPSR1 (0.90) | RAB9ANPC1NPSR1MAPTALDH1A1 | |
| Benzophenone SCHEMBL28148992 | 0.65 | MAOA (0.65) | RAB9ANPC1NPSR1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |