Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13048616 | 0.85 | L3MBTL1 (0.50) | THRBKMT2ANPC1ACHEALDH1A1 | |
| SCHEMBL21170004 | 0.83 | THRB (0.47) | THRBKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL11225929 | 0.83 | THRB (0.47) | THRBKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL18869516 | 0.81 | THRB (0.46) | THRBKMT2ANPC1ACHEALDH1A1 | |
| SCHEMBL27590352 | 0.81 | THRB (0.46) | THRBKMT2ANPC1MEN1ACHE | |
| SCHEMBL11614660 | 0.79 | ACHE (0.47) | KMT2ANPC1MEN1CASP3SENP8 | |
| SCHEMBL5682633 | 0.79 | ACHE (0.61) | KMT2AMEN1ACHEALDH1A1KDM4E | |
| SCHEMBL14889207 | 0.79 | ALDH1A1 (0.62) | THRBNPC1ALDH1A1CYP3A4RAB9A | |
| SCHEMBL28470559 | 0.79 | TUBB1 (0.49) | THRBKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL31648375 | 0.79 | TUBB1 (0.49) | THRBKMT2ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101786-B | Method for synthesizing phenoxyalkenyl ether compound by catalyzing palladium salt | 西南大学 | 2020-09-22 | — | — | CN | disclosed |
| US-4772658-A | ADDITION POLYMERIZATION, POLYISOCYANATE-UNSATURATED ALCOHOL ADDUCT, POLYURETHANES, MOLDINGS | THE DOW CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |