Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 7/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.40 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770629 | 0.87 | TNKS (0.42) | CYP1A1CYP1A2CYP1B1TNKSTNKS2 | |
| SCHEMBL10694328 | 0.83 | ELANE (0.42) | RXFP1TNKSTNKS2PARP1KDM4E | |
| SCHEMBL10696216 | 0.81 | PARP1 (0.44) | RXFP1PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL9533817 | 0.81 | TNKS (0.43) | CYP1A1CYP1A2CYP1B1TNKSTNKS2 | |
| SCHEMBL10694920 | 0.79 | ELANE (0.47) | RXFP1KDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL9536686 | 0.79 | KDM4E (0.59) | CYP1A1CYP1A2CYP1B1RXFP1TNKS | |
| SCHEMBL9533606 | 0.73 | TNKS (0.43) | CYP1A1CYP1A2CYP1B1TNKSTNKS2 | |
| SCHEMBL9534241 | 0.72 | PKM (0.50) | CYP1A1CYP1A2CYP1B1TNKSTNKS2 | |
| SCHEMBL7571452 | 0.72 | HRH3 (0.50) | CYP1A1CYP1A2CYP1B1TNKSTNKS2 | |
| SCHEMBL10695331 | 0.70 | PDE7A (0.43) | TNKSTNKS2PARP1PARP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |