SCHEMBL10695037

SCHEMBL10695037

Nc1cc(S(=O)(=O)Nc2ccccc2C(=O)O)ccc1Cl

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.73
KMT2A Q03164 7/20 0.73
LMNA P02545 1/20 0.73
SLC25A1 P53007 1/20 0.68
KDM4E B2RXH2 4/20 0.64
POLB P06746 1/20 0.64
ACLY P53396 1/20 0.59
ALDH1A1 P00352 4/20 0.58
HSD17B10 Q99714 2/20 0.58
PLG P00747 1/20 0.57
PLAU P00749 1/20 0.57
GAA P10253 2/20 0.55
TP53 P04637 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
MIF P14174 1/20 0.55
CCR2 P41597 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27770307 0.88 MEN1 (0.78) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL34475240 0.88 MEN1 (0.78) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL13577027 0.86 LMNA (0.62) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL2605789 0.85 MEN1 (0.78) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL29688017 0.85 MEN1 (0.78) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL11026493 0.85 MEN1 (0.72) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL5737217 0.83 GAA (0.66) MEN1KMT2ALMNAKDM4EGAA
SCHEMBL11410794 0.83 MEN1 (0.73) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL29918322 0.81 SLC25A1 (1.00) MEN1KMT2ALMNASLC25A1KDM4E
SCHEMBL30777865 0.81 SLC25A1 (1.00) MEN1KMT2ALMNASLC25A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
EP-0112285-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1987-03-18 EP disclosed
EP-0112285-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed