Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | MIF | P14174 | 1/20 | 0.64 |
| ▸ | ACLY | P53396 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34475240 | 0.91 | MEN1 (0.78) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL10695037 | 0.88 | MEN1 (0.73) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL5598171 | 0.84 | SLC25A1 (1.00) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL30777865 | 0.84 | SLC25A1 (1.00) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL29918322 | 0.84 | SLC25A1 (1.00) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL30000258 | 0.84 | SLC25A1 (1.00) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL13856753 | 0.84 | MEN1 (1.00) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL12200779 | 0.84 | CCR2 (0.73) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL11026493 | 0.83 | MEN1 (0.72) | MEN1KMT2ALMNASLC25A1KDM4E | |
| SCHEMBL11862064 | 0.83 | MEN1 (0.72) | MEN1KMT2ALMNASLC25A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646647-A | New methylenebisphenyl compounds useful in the treatment of inflammation | BIOLIPOX AB SE | 2010-02-10 | — | — | CN | disclosed |