Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | CBX7 | O95931 | 1/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.39 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.39 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701198 | 0.90 | TNKS2 (0.44) | TNKS2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10700273 | 0.88 | TNKS2 (0.43) | TNKS2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10700232 | 0.88 | TNKS2 (0.43) | TNKS2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10696397 | 0.87 | ALDH1A1 (0.40) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL10693698 | 0.83 | KDM4E (0.40) | ALDH1A1KDM4ESCN9A | |
| SCHEMBL10696091 | 0.83 | TDP1 (0.54) | TNKS2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10695278 | 0.83 | TNKS2 (0.48) | TNKS2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL10697356 | 0.82 | MEN1 (0.40) | MEN1KMT2AGAAALDH1A1KDM4E | |
| SCHEMBL10695289 | 0.81 | SCN9A (0.34) | MEN1KMT2AGAAMAPTSCN9A | |
| SCHEMBL10696042 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4EL3MBTL1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |