Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696397 | 0.97 | ALDH1A1 (0.40) | KDM4EALDH1A1HSD17B10CYP19A1 | |
| SCHEMBL10696042 | 0.92 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10CYP19A1 | |
| SCHEMBL10696613 | 0.89 | AURKA (0.40) | KDM4EALDH1A1HSD17B10CYP19A1 | |
| SCHEMBL10695491 | 0.87 | MAPT (0.42) | KDM4EALDH1A1SCN9ACNR2 | |
| SCHEMBL10698603 | 0.86 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10698037 | 0.85 | ALDH1A1 (0.38) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10697356 | 0.85 | MEN1 (0.40) | KDM4EALDH1A1HSD17B10CYP19A1SCN9A | |
| SCHEMBL10695289 | 0.84 | SCN9A (0.34) | SCN9ACNR2 | |
| SCHEMBL10696477 | 0.84 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10695087 | 0.83 | TNKS2 (0.44) | KDM4EALDH1A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |