Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697005 | 0.93 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL10695201 | 0.82 | SCN9A (0.35) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL10693698 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1SCN9ACNR2 | |
| SCHEMBL10695728 | 0.80 | MAPT (0.39) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL10695491 | 0.78 | MAPT (0.42) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL10696397 | 0.78 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL10697356 | 0.78 | MEN1 (0.40) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL10695114 | 0.78 | SCN9A (0.37) | KDM4EALDH1A1HPGDMEN1MAPT | |
| SCHEMBL10695289 | 0.77 | SCN9A (0.34) | MEN1MAPTKMT2ASCN9ACNR2 | |
| SCHEMBL10696477 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1HPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |