Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695367 | 0.93 | KDM4E (0.42) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10696042 | 0.81 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDHSD17B10PGR | |
| SCHEMBL10699769 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10696318 | 0.77 | KDM4E (0.41) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10695728 | 0.77 | MAPT (0.39) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10696440 | 0.76 | MEN1 (0.40) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL10701189 | 0.75 | HSD17B10 (0.41) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL10696397 | 0.74 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10695201 | 0.74 | SCN9A (0.35) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL10566335 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |