Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 7/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304561 | 0.81 | P2RX3 (0.36) | ALDH1A1P2RX3EZH2DDR1MAPT | |
| SCHEMBL7470706 | 0.79 | P2RX3 (0.39) | P2RX3 | |
| SCHEMBL8818440 | 0.74 | BCAT1 (0.50) | BCAT1BCAT2ALDH1A1KDM4EDDR1 | |
| SCHEMBL10696215 | 0.72 | HSP90AA1 (0.43) | BCAT1BCAT2ALDH1A1KDM4EDDR1 | |
| SCHEMBL8820735 | 0.71 | ALDH1A1 (0.43) | BCAT1BCAT2ALDH1A1KDM4EDDR1 | |
| SCHEMBL8308409 | 0.71 | ALDH1A1 (0.35) | ALDH1A1KDM4EP2RX3DDR1MAPT | |
| SCHEMBL6802264 | 0.71 | BCAT2 (0.42) | BCAT1BCAT2ALDH1A1KDM4EDDR1 | |
| SCHEMBL10530894 | 0.70 | BCAT1 (0.52) | BCAT1BCAT2SMN1; SMN2 | |
| SCHEMBL8525560 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8309156 | 0.69 | DDR1 (0.32) | ALDH1A1DDR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891336-B1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AG (DE) | 2002-06-05 | — | — | EP | disclosed |
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |