Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696215 | 0.73 | HSP90AA1 (0.43) | ALDH1A1KDM4EHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL27445825 | 0.68 | TRPA1 (0.52) | TRPA1KDM4EMETAP2MAPK1 | |
| SCHEMBL8525560 | 0.68 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1CYP2C9CYP2C19 | |
| SCHEMBL8820735 | 0.67 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL8551841 | 0.66 | ALDH1A1 (0.33) | ALDH1A1KDM4ECYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL24337912 | 0.66 | CHEK1 (0.44) | MKNK1TRPA1ALDH1A1KDM4EMETAP2 | |
| SCHEMBL9237639 | 0.65 | MAOB (0.44) | — | |
| SCHEMBL4782024 | 0.65 | TRAP1 (0.38) | ALDH1A1KDM4EHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL17240320 | 0.65 | TRAP1 (0.36) | ALDH1A1KDM4EHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL6802264 | 0.64 | BCAT2 (0.42) | ALDH1A1KDM4EHSP90AA1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012884-A1 | HERBICIDAL 6-HETEROCYCLIC INDAZOLE DERIVATIVES | FMC CORPORATION (US) | 1997-04-10 | — | — | WO | disclosed |