Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698024 | 0.90 | THRB (0.38) | TXNRD1TDP1KMT2AKDM4EMERTK | |
| SCHEMBL6641789 | 0.76 | TXNRD1 (0.56) | TXNRD1MAPTPTGS2 | |
| SCHEMBL20471446 | 0.75 | TXNRD1 (0.50) | TXNRD1MAPT | |
| SCHEMBL20471458 | 0.75 | TXNRD1 (0.39) | TXNRD1TDP1KMT2AMERTKMAPT | |
| SCHEMBL10697964 | 0.74 | KDM4E (0.40) | TDP1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL6639747 | 0.74 | MERTK (0.54) | TXNRD1TDP1KMT2AKDM4EMERTK | |
| SCHEMBL6644384 | 0.72 | TDP1 (0.31) | TXNRD1TDP1KMT2AMAPTMEN1 | |
| SCHEMBL27631561 | 0.70 | PTGS2 (0.53) | TDP1KMT2AKDM4EMAPTPTGS2 | |
| SCHEMBL10699015 | 0.69 | TDP1 (0.42) | TXNRD1TDP1KMT2AMAPTPOLB | |
| SCHEMBL10697439 | 0.68 | MEN1 (0.38) | TXNRD1TDP1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |