SCHEMBL170251

SCHEMBL170251

C=Cc1c[nH]c(=O)[nH]c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPYD Q12882 5/20 1.00
MAPT P10636 3/20 0.46
GAA P10253 3/20 0.46
ALDH1A1 P00352 2/20 0.46
LMNA P02545 2/20 0.46
ATAD2 Q6PL18 1/20 0.46
CYP19A1 P11511 1/20 0.46
TSHR P16473 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
HTT P42858 1/20 0.46
HBB P68871 1/20 0.46
PMP22 Q01453 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP3A4 P08684 1/20 0.37
KDM4C Q9H3R0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Vinylphenol SCHEMBL28409703 0.83 DPYD (0.69) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL48228 0.79 DPYD (0.65) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL1916591 0.77 DPYD (0.63) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL28624115 0.77 DPYD (0.62) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL6374582 0.74 DPYD (0.59) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL15798473 0.74 DPYD (0.62) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL6374591 0.74 DPYD (0.59) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL65892 0.74 DPYD (0.62) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL933037 0.74 DPYD (0.59) DPYDMAPTGAAALDH1A1LMNA
SCHEMBL190377 0.74 DPYD (0.59) DPYDMAPTGAAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 578 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-20240117431-A1 STEM-CELL BASED BIOMARKER DISCOVERY UNIV CALIFORNIA (US) 2024-04-11 US claimed
CN-111268842-B Sewage treatment method 濮阳市盛源能源科技股份有限公司 2022-05-20 CN claimed
CN-111303612-B Blue-light-proof polyurethane optical resin material 万华化学集团股份有限公司 2022-02-15 CN claimed
CN-111268842-A Sewage treatment method 濮阳市盛源能源科技股份有限公司 2020-06-12 CN claimed
US-9822326-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-11-21 US claimed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 US claimed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US claimed
EP-3157572-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
EP-0726904-A1 5-FLUOROURACIL DERIVATIVES THE WELLCOME FOUNDATION LIMITED (GB) 1996-08-21 EP claimed
EP-0494370-B1 Antiviral (phosphonomethoxy)methoxy purine/pyrimidine derivatives ACAD OF SCIENCE CZECH REPUBLIC (CS) 1995-06-28 EP claimed
WO-1995012606-A1 5-FLUOROURACIL DERIVATIVES THE WELLCOME FOUNDATION LIMITED (GB) 1995-05-11 WO claimed
US-5386030-A Chemical intermediates INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCE OF THE CZECH REPUBLIC (CZ) 1995-01-31 US claimed
EP-0630381-A4 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. 1995-01-04 EP claimed
EP-0630381-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. ACAD OF SCIENCE CZECH REPUBLIC (CS) 1994-12-28 EP claimed
US-5208221-A Nucleotides and intermediates for herpes virus or leukemia virus BRISTOL-MYERS SQUIBB COMPANY (US) 1993-05-04 US claimed
WO-1993007157-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1993-04-15 WO claimed
US-5126506-A Deoxygenation at 3-position of furan ring BRISTOL-MYERS COMPANY (US) 1992-06-30 US claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 DPYD 369/4885MAPT 3589/4885GAA 554/4885
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 DPYD 369/4885MAPT 3589/4885GAA 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.