Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319436 | 0.86 | GABRA1 (0.60) | SMN1; SMN2RAB9ALMNATP53ALDH1A1 | |
| SCHEMBL9319102 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ALMNATP53ALDH1A1 | |
| SCHEMBL1200586 | 0.73 | SMN1; SMN2 (0.71) | SMN1; SMN2RAB9ALMNATP53ALDH1A1 | |
| SCHEMBL29324417 | 0.70 | GABRA1 (0.58) | TP53ALDH1A1GABRA1GABRB2GABRB1 | |
| SCHEMBL1075376 | 0.69 | ALDH1A1 (0.61) | SMN1; SMN2RAB9ALMNATP53ALDH1A1 | |
| SCHEMBL12611037 | 0.68 | RAB9A (0.66) | SMN1; SMN2RAB9ALMNATP53ALDH1A1 | |
| SCHEMBL28289153 | 0.67 | GABRA1 (0.69) | TP53ALDH1A1GABRA1GABRB2GABRB1 | |
| SCHEMBL17417665 | 0.67 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ALMNATP53ALDH1A1 | |
| SCHEMBL11010279 | 0.66 | KDM4E (0.49) | SMN1; SMN2RAB9ALMNATP53ALDH1A1 | |
| SCHEMBL1973248 | 0.65 | HTR3E (0.54) | RAB9ALMNAALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764518-A | Antibacterial agents containing oxo-4-pyridine carboxylic acid derivatives | PANMEDICA (FR) | 1988-08-16 | — | — | US | disclosed |