Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CDA | P32320 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 3/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414315 | 0.87 | ALDH1A1 (0.45) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL16781797 | 0.80 | MAPT (0.51) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL7764746 | 0.80 | MAPT (0.51) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL31685622 | 0.80 | MAPT (0.51) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL7640658 | 0.79 | MAPT (0.47) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL5903970 | 0.79 | PYGM (0.49) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL635155 | 0.79 | MAPT (0.47) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL5903974 | 0.79 | PYGM (0.49) | MAPTCDAPYGMSLC28A1SLC28A2 | |
| SCHEMBL7612678 | 0.78 | TYMP (0.53) | MAPTCDAPYGMTYMP | |
| SCHEMBL12039570 | 0.78 | P2RY2 (0.38) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295090-A2 | Chemical process | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-12-14 | — | — | EP | disclosed |