Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.56 |
| ▸ | MMP12 | P39900 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 2/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788040 | 0.86 | MMP1 (0.59) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL2760714 | 0.85 | MMP1 (0.61) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL7784368 | 0.85 | CA1 (0.70) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL359770 | 0.82 | MMP1 (0.79) | MMP1MMP12GAAALDH1A1MMP2 | |
| SCHEMBL11568507 | 0.80 | MMP1 (0.56) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL13758640 | 0.79 | HSD11B1 (0.56) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL3239227 | 0.79 | ALDH1A1 (0.71) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL6362669 | 0.79 | MMP1 (0.47) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL5450999 | 0.79 | ALDH1A1 (0.63) | MMP1MMP12GAAALDH1A1KEAP1 | |
| SCHEMBL2969958 | 0.78 | MMP1 (0.59) | MMP1MMP12GAAALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897970-B1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-07-13 | — | — | EP | claimed |
| US-20150210729-A1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2015-07-30 | — | — | US | claimed |
| EP-2897970-A1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2015-07-29 | — | — | EP | claimed |
| WO-2014044645-A1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2014-03-27 | — | — | WO | claimed |
| EP-2897970-B1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2016-07-13 | — | — | EP | disclosed |
| US-20150210729-A1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2015-07-30 | — | — | US | disclosed |
| EP-2897970-A1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2015-07-29 | — | — | EP | disclosed |
| WO-2014044645-A1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2014-03-27 | — | — | WO | disclosed |
| EP-0284099-A2 | Silver halide color photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210729-A1 | MACROLIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | PCSK9, CYP51A1, ABCB11 | MMP1 2904/4885MMP12 636/4885GAA 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.