Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633784 | 0.84 | ALDH1A1 (0.56) | CA2ALDH1A1HPGDMEN1USP2 | |
| SCHEMBL25418726 | 0.81 | ALDH1A1 (0.53) | CA2ALDH1A1HPGDMEN1USP2 | |
| SCHEMBL10576775 | 0.77 | CA2 (0.61) | CA2ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL32895 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12 | |
| SCHEMBL32681985 | 0.74 | CA2 (1.00) | CA2CA1CA9CA12 | |
| SCHEMBL3433646 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HPGDMEN1USP2KMT2A | |
| SCHEMBL3140093 | 0.71 | LMNA (0.68) | CA2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL28669933 | 0.70 | ALDH1A1 (0.55) | ALDH1A1HPGDMEN1USP2KMT2A | |
| SCHEMBL3149535 | 0.69 | LMNA (0.71) | CA2ALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL30494604 | 0.68 | ALDH1A1 (0.53) | ALDH1A1HPGDMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293716-A2 | Polyhydrobenz(c,d)indolsulfonamides | BAYER AG (DE) | 1988-12-07 | — | — | EP | claimed |