Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10704460 | 0.83 | SRD5A2 (0.52) | AKR1B1CA1CA2EGFRSIRT1 | |
| SCHEMBL10704144 | 0.83 | AKR1B1 (0.58) | AKR1B1EGFR | |
| SCHEMBL10710964 | 0.80 | P4HB (0.66) | P4HB | |
| SCHEMBL10710969 | 0.80 | P4HB (0.66) | P4HB | |
| SCHEMBL10706677 | 0.80 | ALDH1A1 (0.52) | AKR1B1EGFRSIRT1HTTPKM | |
| SCHEMBL10707197 | 0.80 | AKR1B1 (0.46) | AKR1B1EGFRSIRT1PKM | |
| SCHEMBL10706602 | 0.80 | SRD5A2 (0.50) | AKR1B1CA2EGFRSIRT1HTT | |
| SCHEMBL10706364 | 0.80 | PKM (0.56) | AKR1B1EGFRSIRT1HTTPKM | |
| SCHEMBL6748653 | 0.79 | SIRT1 (0.54) | GSK3BCA1CA2EGFRP4HB | |
| SCHEMBL25908752 | 0.76 | AKR1B1 (0.47) | PTGDR2AKR1B1EGLN1HTTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150166-B1 | NOVEL ARYLACITIC ACID DERIVATIVES | PHARMACIA AB (SE) | 1988-07-20 | — | — | EP | disclosed |
| US-4695648-A | PROSTAGLANDIN DEHYDROGENASE INHIBITORS | PHARMACIA AB (SE) | 1987-09-22 | — | — | US | disclosed |
| EP-0168467-A1 | NOVEL ARYLACETIC ACID DERIVATIVES | PHARMACIA AB (SE) | 1986-01-22 | — | — | EP | disclosed |
| WO-1985003287-A1 | NOVEL ARYLACETIC ACID DERIVATIVES | PHARMACIA AB (SE) | 1985-08-01 | — | — | WO | disclosed |
| EP-0150166-A1 | Novel arylacitic acid derivatives | PHARMACIA AB (SE) | 1985-07-31 | — | — | EP | disclosed |