SCHEMBL7778608

SCHEMBL7778608

CCOP(c1ccc(F)cc1)c1ccc(F)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2D6 P10635 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ACHE P22303 1/20 0.35
LMNA P02545 3/20 0.34
PTBP1 P26599 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP2C9 P11712 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
IDO1 P14902 3/20 0.32
AGXT P21549 2/20 0.32
CASP3 P42574 1/20 0.32
TRPV1 Q8NER1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10709571 0.79 ACHE (0.38) TDP1CYP1A2CYP2C19ACHELMNA
SCHEMBL11277499 0.77 LMNA (0.36) TDP1CYP1A2LMNASMN1; SMN2MEN1
SCHEMBL196443 0.76 CYP3A4 (0.39) TDP1L3MBTL1NPSR1TP53
SCHEMBL7776013 0.75 ACHE (0.39) ACHELMNAMAPTIDO1AGXT
SCHEMBL8638036 0.74 ALDH1A1 (0.46) TDP1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL8638207 0.73 NFE2L2 (0.44) CYP1A2CYP2C19CYP2D6L3MBTL1LMNA
SCHEMBL16286430 0.70 CYP1A2 (0.42) TDP1CYP1A2CYP2C19CYP2D6L3MBTL1
SCHEMBL11728040 0.70 KCNN4 (0.33) TDP1TP53
SCHEMBL8336303 0.69 ALDH1A1 (0.40) TDP1CYP1A2CYP2C19L3MBTL1LMNA
SCHEMBL25199142 0.67 ALDH1A1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN claimed
EP-0673944-B1 Process for preparing 2,2'-bis(diphenyl-phosphinylmethyl)-1,1'binaphtyl and novel compounds belonging to this group of substances CELANESE CHEM EUROPE GMBH (DE) 2001-08-16 EP claimed
US-5767317-A Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-16 US claimed
US-5756848-A Process for preparing secondary arylphosphine oxides HOECHST AKTIENGESELLSCHAFT 1998-05-26 US claimed
CN-119504845-A Method for preparing S- (4- (2, 2-diaryl vinyl) thio-butyl) selenium/tellurium phosphorus/phosphonate 湖南理工学院 2025-02-25 CN disclosed
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN disclosed
CN-115925743-A Method for preparing (2-oxo-2-aryl ethyl) diaryl phosphine oxide compound 湖南理工学院 2023-04-07 CN disclosed
US-5767317-A Process for preparing 2,2'-bis(diphenylphosphinylmethyl)-1,1'-binaphthyls and new compounds from this class of substances HOECHST AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
US-5756848-A Process for preparing secondary arylphosphine oxides HOECHST AKTIENGESELLSCHAFT 1998-05-26 US disclosed