Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1403874 | 0.98 | CTSB (0.50) | POLBSIGMAR1CTSBCTSSCTSL | |
| SCHEMBL4400570 | 0.82 | CTSB (0.56) | POLBCTSBCTSSCTSLCYP2C9 | |
| SCHEMBL3662863 | 0.82 | SMN1; SMN2 (0.50) | KMT2ACTSK | |
| SCHEMBL4583683 | 0.80 | POLB (0.65) | POLBSIGMAR1MMP8EPHX2CYP2D6 | |
| SCHEMBL10707874 | 0.80 | CTSS (0.43) | CTSBCTSSCTSLCTSK | |
| SCHEMBL12333754 | 0.78 | SIGMAR1 (0.58) | POLBSIGMAR1MMP8CYP2D6CYP2C9 | |
| SCHEMBL25384603 | 0.77 | FAAH (0.62) | POLB | |
| SCHEMBL1143391 | 0.76 | CTSL (0.51) | CTSBCTSSCTSLKMT2AL3MBTL1 | |
| SCHEMBL4961185 | 0.76 | SIGMAR1 (0.62) | POLBSIGMAR1MMP8KMT2A | |
| SCHEMBL14598324 | 0.75 | MAPT (0.52) | CTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4767744-A | Substituted tyrosyl methionyl dipeptide amides | G. D. SEARLE & CO. (US) | 1988-08-30 | — | — | US | disclosed |