Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711888 | 0.85 | BRD4 (0.40) | HDAC4HDAC2HDAC8MAPTALDH1A1 | |
| SCHEMBL10711944 | 0.80 | CREBBP (0.46) | GAAEDNRBEDNRAPTPN1TP53 | |
| SCHEMBL10712632 | 0.80 | PGR (0.39) | MAPTCYP3A4SMN1; SMN2PTGS2TTR | |
| SCHEMBL1321330 | 0.77 | HTR2C (0.46) | MAPTALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL10713399 | 0.77 | PGR (0.36) | MAPTALDH1A1EDNRBEDNRACYP2C9 | |
| SCHEMBL10712953 | 0.74 | IDO1 (0.35) | MAPTALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL10712822 | 0.74 | ALDH1A1 (0.40) | MAPTALDH1A1GAACYP2C9SMN1; SMN2 | |
| SCHEMBL10713959 | 0.73 | PGR (0.40) | HDAC4HDAC2HDAC8MAPTALDH1A1 | |
| SCHEMBL11094086 | 0.73 | HTR1A (0.34) | ALDH1A1GAACYP3A4CYP2C9 | |
| SCHEMBL11368672 | 0.72 | DAO (0.40) | MAPTALDH1A1GAABACE1CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |