Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 7/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10711127 | 0.86 | GSK3B (0.36) | GSK3BMAPTTDP1POLBCYP3A4 | |
| SCHEMBL10714044 | 0.83 | TRPM2 (0.38) | GSK3BMEN1KMT2APGRLMNA | |
| SCHEMBL10712632 | 0.82 | PGR (0.39) | GSK3BMAPTTDP1MEN1KMT2A | |
| SCHEMBL10715084 | 0.81 | PTGS2 (0.39) | GSK3BMAPTTDP1MEN1KMT2A | |
| SCHEMBL10713691 | 0.79 | GSK3B (0.40) | GSK3BMAPTTDP1MEN1KMT2A | |
| SCHEMBL10711924 | 0.78 | PGR (0.38) | GSK3BMAPTTDP1CYP3A4GSK3A | |
| SCHEMBL10713389 | 0.74 | PGR (0.55) | GSK3BMAPTTDP1MEN1KMT2A | |
| SCHEMBL10711141 | 0.74 | CYP3A4 (0.38) | GSK3BMAPTTDP1MEN1KMT2A | |
| SCHEMBL19370850 | 0.71 | PGR (0.50) | TDP1MEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL11427311 | 0.71 | PGR (0.50) | TDP1MEN1KMT2ACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |