Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10713691 | 0.87 | GSK3B (0.40) | PGRGSK3BCA12CA1CA2 | |
| SCHEMBL10711127 | 0.82 | GSK3B (0.36) | PGRGSK3BCA12CA9TDP1 | |
| SCHEMBL10713389 | 0.80 | PGR (0.55) | PGRGSK3BCA12CA1CA2 | |
| SCHEMBL10712219 | 0.78 | GSK3B (0.38) | PGRGSK3BTDP1CYP3A4ADORA2A | |
| SCHEMBL10713193 | 0.76 | CRHBP (0.44) | PGRGSK3BTDP1ALDH1A1MAPT | |
| SCHEMBL10712632 | 0.76 | PGR (0.39) | PGRGSK3BTDP1CYP3A4ADORA2A | |
| SCHEMBL10711518 | 0.75 | MAPK1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL10711646 | 0.74 | MEN1 (0.38) | PGRTDP1CYP3A4ALDH1A1MAPT | |
| SCHEMBL10712895 | 0.74 | MEN1 (0.38) | PGRGSK3BTDP1CYP3A4ALDH1A1 | |
| SCHEMBL10715084 | 0.72 | PTGS2 (0.39) | PGRGSK3BTDP1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670566-A | ANTIIFLAMMATORY AGENTS, ANTICOAGULANTS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1987-06-02 | — | — | US | disclosed |
| US-4440785-A | Methods of using 2-aminobiphenylacetic acids, esters, and metal salts thereof to treat inflammation | A. H. ROBINS COMPANY, INC. (US) | 1984-04-03 | — | — | US | disclosed |