Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSH | P09668 | 1/20 | 0.31 |
| ▸ | CTSC | P53634 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | CPB1 | P15086 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422486 | 0.89 | LNPEP (0.35) | LNPEP | |
| SCHEMBL10421180 | 0.85 | CTSS (0.42) | CTSK | |
| SCHEMBL10420913 | 0.82 | REN (0.46) | — | |
| Hydrochloric Acid SCHEMBL10704612 | 0.78 | TDP1 (0.31) | LNPEPCPB1CPB2 | |
| SCHEMBL10422480 | 0.76 | REN (0.45) | — | |
| SCHEMBL9740788 | 0.76 | POLB (0.34) | CTSCCTSK | |
| SCHEMBL30799721 | 0.72 | LTA4H (0.47) | CTSCCPB2 | |
| SCHEMBL6434283 | 0.71 | MAP3K7 (0.32) | — | |
| SCHEMBL6434286 | 0.71 | MAP3K7 (0.32) | — | |
| SCHEMBL7282601 | 0.71 | REN (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281316-A2 | Renin inhibitors | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |