Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | REN | P00797 | 5/20 | 0.44 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 4/20 | 0.41 |
| ▸ | ECE1 | P42892 | 4/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | NMBR | P28336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718415 | 1.00 | CTSL (0.44) | CTSLRENCTSKCTSSCTSB | |
| SCHEMBL10718460 | 0.88 | REN (0.47) | CTSLRENCTSKCTSSCTSB | |
| SCHEMBL7283367 | 0.87 | ACE2 (0.51) | RENMMEECE1ACE | |
| SCHEMBL7284698 | 0.87 | ACE2 (0.51) | RENMMEECE1ACE | |
| SCHEMBL7308401 | 0.86 | ECE1 (0.53) | RENMMEECE1ACE | |
| SCHEMBL7282841 | 0.83 | REN (0.45) | CTSLRENMMEECE1 | |
| SCHEMBL7283203 | 0.81 | CTSL (0.43) | CTSLRENCTSSCTSBMME | |
| SCHEMBL7274969 | 0.81 | CTSL (0.45) | CTSLRENCTSKCTSSCTSB | |
| SCHEMBL7286158 | 0.80 | MMP2 (0.48) | CTSLRENCTSKCTSBMME | |
| SCHEMBL10718613 | 0.80 | CTSL (0.45) | CTSLRENCTSKCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209848-A2 | Enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | claimed |