Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.68 |
| ▸ | ECE1 | P42892 | 4/20 | 0.56 |
| ▸ | MME | P08473 | 3/20 | 0.56 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KYNU | Q16719 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10746815 | 0.91 | ACE2 (0.71) | ACE2ECE1MMECTSKCTSS | |
| SCHEMBL8278084 | 0.88 | ECE1 (0.62) | ACE2ECE1MME | |
| SCHEMBL15397862 | 0.86 | ACE2 (0.71) | ACE2ECE1MMECTSKCTSS | |
| SCHEMBL9645985 | 0.84 | ACE2 (0.68) | ACE2ECE1MMECTSKCTSS | |
| SCHEMBL10717382 | 0.81 | CTSL (0.52) | ACE2ECE1MMECTSKCTSS | |
| SCHEMBL9296026 | 0.78 | ACE2 (0.53) | ACE2ECE1MMECTSKCTSS | |
| SCHEMBL9715136 | 0.78 | ACE2 (0.69) | ACE2ECE1MMEHSD17B10 | |
| SCHEMBL23881812 | 0.78 | ACE2 (0.52) | ACE2ECE1MMEKYNU | |
| SCHEMBL9697212 | 0.77 | ECE1 (0.52) | ACE2ECE1MMEKYNU | |
| SCHEMBL10985006 | 0.77 | CTSK (0.58) | CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |