Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 16/20 | 0.62 |
| ▸ | MME | P08473 | 15/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718516 | 0.88 | ACE2 (0.68) | ECE1MMEACE2 | |
| SCHEMBL6928745 | 0.84 | ECE1 (0.77) | ECE1MMEACE2MMP8MMP14 | |
| SCHEMBL7397375 | 0.84 | ECE1 (0.59) | ECE1MMEACE2F2PLAU | |
| SCHEMBL7291199 | 0.83 | ECE1 (0.61) | ECE1MMEACE2F2PLAU | |
| SCHEMBL14334539 | 0.83 | ECE1 (0.63) | ECE1MMEACE2F2PLAU | |
| SCHEMBL7328702 | 0.83 | ECE1 (0.63) | ECE1MMEACE2F2PLAU | |
| SCHEMBL10717382 | 0.82 | CTSL (0.52) | ECE1MMEACE2 | |
| SCHEMBL17337467 | 0.82 | KMT2A (0.51) | PLAU | |
| SCHEMBL7397132 | 0.82 | F2 (0.65) | ECE1MMEACE2F2PLAU | |
| SCHEMBL6928069 | 0.81 | ACE2 (0.81) | ECE1MMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | disclosed |