Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716650 | 0.84 | MAPT (0.78) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10717891 | 0.83 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10717698 | 0.80 | MAPT (0.72) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11787832 | 0.77 | RECQL (0.49) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10732434 | 0.77 | NPC1 (0.47) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL10716463 | 0.75 | MAPT (0.64) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL10727301 | 0.72 | KMT2A (0.47) | KMT2AMEN1ALDH1A1HTTHPGD | |
| SCHEMBL10727300 | 0.72 | KMT2A (0.47) | KMT2AMEN1ALDH1A1HTTHPGD | |
| SCHEMBL7257538 | 0.72 | ALDH1A1 (0.81) | MAPTKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL7257543 | 0.72 | ALDH1A1 (0.81) | MAPTKMT2AMEN1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |