Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717698 | 0.84 | MAPT (0.72) | MAPTKMT2AMEN1LMNAGAA | |
| SCHEMBL10716650 | 0.82 | MAPT (0.78) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL10717891 | 0.78 | MAPT (1.00) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL10719158 | 0.75 | MAPT (0.71) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL5163794 | 0.72 | LMNA (0.62) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL10717722 | 0.71 | MAPT (0.53) | MAPTKMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL10716583 | 0.70 | MAPT (0.56) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL10716377 | 0.70 | MAPT (0.56) | MAPTKMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL10726134 | 0.70 | MAPT (0.49) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL10726778 | 0.69 | MAPT (0.51) | MAPTKMT2AMEN1PKMCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |