Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA4 | P22748 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716650 | 0.88 | MAPT (0.78) | MAPTMEN1KMT2ACA2CA1 | |
| SCHEMBL10716463 | 0.84 | MAPT (0.64) | MAPTMEN1KMT2ACA2CA1 | |
| SCHEMBL10717891 | 0.84 | MAPT (1.00) | MAPTMEN1KMT2ACA2CA1 | |
| SCHEMBL10725846 | 0.81 | ALDH1A1 (0.54) | MAPTMEN1KMT2ACA2CA1 | |
| SCHEMBL10719158 | 0.80 | MAPT (0.71) | MAPTMEN1KMT2APKMALDH1A1 | |
| SCHEMBL10726650 | 0.77 | MEN1 (0.53) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10730945 | 0.75 | PKM (0.58) | MAPTMEN1KMT2ACA2CA1 | |
| SCHEMBL10718981 | 0.74 | ALDH1A1 (0.43) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10716561 | 0.74 | CASP3 (0.52) | MAPTMEN1KMT2ACA2CA1 | |
| SCHEMBL11783528 | 0.73 | MAPT (0.43) | MAPTMEN1KMT2ACA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659727-A | ANTIARTHRITIC AGENTS | MAY & BAKER LIMITED (GB) | 1987-04-21 | — | — | US | disclosed |
| EP-0174832-A2 | Ethene derivatives | MAY & BAKER LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |